Astellas Pharma is one of Japan's leading pharmaceutical companies, now developing a growing international profile. Its top-selling drug for the past few years has been the prostate cancer treatment Xtandi, sold in more than 70 countries, backed by supporting products Eligard and Gonax. Other key medicines include Vesicare for over-active bladder and its successor Myrbetriq/Betmiga, and transplantation drug Prograf. It also owns lung cancer drug Tarceva, which is co-promoted by Roche/Genentech in Europe and the US. In its domestic market it has local rights to several well-known drugs including Pfizer's Lipitor, and AstraZeneca's Seroquel and Symbicort, and agreed a Japanese joint venture in 2013 with US biotech giant Amgen. Astellas Pharma was created in 2005 from the merger of two existing Japanese drug companies, Yamanouchi Pharmaceutical (estbalished 1923) and Fujisawa Pharmaceutical (which traced its heritage back to 1894). Global revenues for year ending Mar 2020 were approximately $11.9bn, with net profit of approx $2.0bn. Top seller was once again Xtandi (up over 20% year-on-year to approx $3.7bn). The over-active bladder franchise contributed a further $1.9bn (although sales of Vesicare alone more than halved during the year), with another $1.8bn from Prograf. Pfizer is now Astellas' co-promotion partner for Xtandi in the US (following its acquisition of original partner and co-developer Medivation). Japan accounted for just under a third of group revenues, but sales from the Americas and EMEA have doubled in five years and now represent more than 60% of the total. Kenji Yasukawa is CEO.
Capsule checked 28th December 2020
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