The global pharmaceutical market was worth $996bn in 2017, up almost 3% on the year before. The US accounted for 45% of that total, or $453bn. Europe contributed a further 21% (or $214bn), and the rest of the established world for 11% (or $112bn). The fastest growth continues to come from emerging markets, where sales rose by almost 8% in 2017 to $216bn. The top five markets by value are the US, Japan, China, Germany and France. Drug development has slowed dramatically as a result of rising costs. Despite a total R&D budget of $154bn in 2016, only 22 new drugs were approved by the US FDA in 2016, fewer than half the year before.

The World's Leading Pharma Companies in 2020 by healthcare revenues

Johnson & Johnson	AstraZeneca
Roche	Bayer
Novartis	Amgen
Merck & Co	Gilead Sciences
AbbVie	Eli Lilly & Co
Glaxo SmithKline	Boehringer Ingelheim
Bristol-Myers Squibb	Novo Nordisk
Pfizer	Teva
Sanofi	Biogen
Takeda	Astellas Pharma

Source: company reports

The World's Top 20 Prescription Drugs in 2020 by global sales

Humira $20.39bn AbbVie	Enbrel $6.37bn Amgen / Pfizer / Takeda
Keytruda $14.38bn Merck	Prevnar $5.95bn Pfizer
Revlimid $12.15bn BMS	Ibrance $5.39bn Pfizer
Eliquis $9.17bn BMS / Pfizer	Avastin $5.32bn Roche
Imbruvica $8.43bn AbbVie / J&J	Trulicity $5.07bn Eli LillyRoche
Eylea $8.36bn Bayer / Regeneron	Ocrevus $4.61bn Roche
Stelara $7.94bn Janssen / J&J	Rituxan / MabThera $4.52bn Roche
Opdivo $7.92bn BMS	Xtandi $4.39bn Astellas Pharma
Biktarvy $7.26bn Gilead Sciences	Tagrisso $4.33bn AstraZeneca
Xarelto $6.93bn Bayer/ J&J	Remicade $4.20bn J&J / Merck / Mitsubishi Tanabe

Source: Fierce Pharma, company reports

The World's Top Consumer Health Companies in 2017

Johnson & Johnson $13.6bn	Reckitt Benckiser $6.9bn
GlaxoSmithKline $10.5bn	Sanofi $4.8bn
Amway $8.6bn	Herbalife $4.4bn
Procter & Gamble $7.5bn	Pfizer $3.5bn
Bayer $7.0bn	Nature's Bounty $3.3bn

Source: Igea, company reports; includes skincare, personal care, oral care, nutritionals, vitamins & hygiene

The World's Top Animal Healthcare Companies in 2014

Zoetis (ex-Pfizer) 20% global share	Merial (Sanofi) 12%
Elanco/Novartis AH (Eli Lilly & Co) 15%	Bayer 7%
Merck & Co 14%	Boehringer Ingelheim 6%

Source: PwC

Top US OTC Products in 2013 by sales

Advil (Pfizer) $615m	Alcon (Novartis) $447m	Dr Scholl's (Merck*) $370m
Nature Made $596m	Claritin (Merck*) $430m	Aleve (Bayer) $364m
Mucinex (Reckitt) $578m	Depend (Kimberly-Clark) $393m	Prilosec OTC (P&G) $359m
Ensure (Abbott) $496m	Poise (Kimberly-Clark) $379m	5 Hour Energy $332m

* Bayer from 2014. Source: Main products including biggest variants; IRI 52 wks to Jan 2014 all channels, Drugstorenews

Other companies profiled in Adbrands

Bausch Health (formerly Valeant)

Abbott Laboratories

Gone But Not (Completely) Forgotten

Warner-Lambert	Smithkline Beecham
Wyeth	Aventis
Schering-Plough	Pharmacia