The global pharmaceutical market was worth $996bn in 2017, up almost 3% on the year before. The US accounted for 45% of that total, or $453bn. Europe contributed a further 21% (or $214bn), and the rest of the established world for 11% (or $112bn). The fastest growth continues to come from emerging markets, where sales rose by almost 8% in 2017 to $216bn. The top five markets by value are the US, Japan, China, Germany and France. Drug development has slowed dramatically as a result of rising costs. Despite a total R&D budget of $154bn in 2016, only 22 new drugs were approved by the US FDA in 2016, fewer than half the year before.

The World's Leading Pharma Companies in 2017 by healthcare revenues

Johnson & Johnson	AbbVie
Roche	Gilead Sciences
Pfizer	Eli Lilly & Co
Novartis	Amgen
Sanofi	AstraZeneca
Merck & Co	Teva
Glaxo SmithKline	Bristol-Myers Squibb
Bayer	Abbott Laboratories

Source: company reports

The World's Top 20 Prescription Drugs in 2015 by global sales

Humira $14.02bn AbbVie	Crestor $5.43bn AstraZeneca / Shionogi
Harvoni $13.86bn Gilead Sciences	Solvadi $5.28bn Gilead Sciences
Enbrel $9.03bn Amgen / Pfizer / Takeda	Seretide / Advair $5.23bn GlaxoSmithKline
Remicade $8.96bn J&J / Merck / Mitsubishi Tanabe	Copaxone $5.21bn Teva
Lantus $7.21bn Sanofi	Neulasta $4.72bn Amgen
Avastin $6.91bn Roche	Gleevec $4.66bn Novartis
Herceptin $6.75bn Roche	Xarelto $4.41bn Bayer/ J&J
Prevnar $6.25bn Pfizer	Spiriva $3.94bn Boehringer Ingelheim
Rituxan / MabThera $5.83bn Roche	Januvia $3.86bn Merck
Revlimid $5.80bn Celgene	Lyrica $3.66bn Pfizer / Eisai

Source: Igea, company reports

The World's Top Consumer Healthcare Companies in 2014

GlaxoSmithKline / Novartis	Reckitt Benckiser
Bayer / Merck	Boehringer Ingelheim
Johnson & Johnson	Procter & Gamble
Sanofi	Taisho
Pfizer	Takeda Pharmaceutical

Source: Bayer

The World's Top Animal Healthcare Companies in 2014

Zoetis (ex-Pfizer) 20% global share	Merial (Sanofi) 12%
Elanco/Novartis AH (Eli Lilly & Co) 15%	Bayer 7%
Merck & Co 14%	Boehringer Ingelheim 6%

Source: PwC

Top US OTC Products in 2013 by sales

Advil (Pfizer) $615m	Alcon (Novartis) $447m	Dr Scholl's (Merck*) $370m
Nature Made $596m	Claritin (Merck*) $430m	Aleve (Bayer) $364m
Mucinex (Reckitt) $578m	Depend (Kimberly-Clark) $393m	Prilosec OTC (P&G) $359m
Ensure (Abbott) $496m	Poise (Kimberly-Clark) $379m	5 Hour Energy $332m

* Bayer from 2014. Source: Main products including biggest variants; IRI 52 wks to Jan 2014 all channels, Drugstorenews

Other companies profiled in Adbrands

Abbott Laboratories	Allergan
Valeant	Takeda
Astellas Pharma

Gone But Not (Completely) Forgotten

Warner-Lambert	Smithkline Beecham
Wyeth	Aventis
Schering-Plough	Pharmacia