The global pharmaceutical market was worth $996bn in 2017, up almost 3% on the year before. The US accounted for 45% of that total, or $453bn. Europe contributed a further 21% (or $214bn), and the rest of the established world for 11% (or $112bn). The fastest growth continues to come from emerging markets, where sales rose by almost 8% in 2017 to $216bn. The top five markets by value are the US, Japan, China, Germany and France. Drug development has slowed dramatically as a result of rising costs. Despite a total R&D budget of $154bn in 2016, only 22 new drugs were approved by the US FDA in 2016, fewer than half the year before.

The World's Leading Pharma Companies in 2018 by healthcare revenues

Johnson & Johnson	Eli Lilly & Co
Roche	Amgen
Pfizer	Bristol-Myers Squibb
Novartis	Gilead Sciences
Merck & Co	AstraZeneca
Glaxo SmithKline	Boehringer Ingelheim
Sanofi	Takeda
AbbVie	Teva
Abbott Laboratories	Novo Nordisk
Bayer	Allergan

Source: company reports

The World's Top 20 Prescription Drugs in 2017 by global sales

Humira $18.43bn AbbVie	Januvia / Janumet $5.90bn Merck
Eylea $8.23bn Bayer / Regeneron	Lantus $5.65bn Sanofi
Revlimid $8.19bn Celgene	Prevnar $5.60bn Pfizer
Rituxan / MabThera $8.11bn Roche	Opdivo $4.95bn BMS
Enbrel $7.98bn Amgen / Pfizer / Takeda	Neulasta / Peglasta $4.56bn Amgen
Herceptin $7.55bn Roche	Lyrica $4.51bn Pfizer / Eisai
Eliquis $7.40bn BMS / Pfizer	Harvoni $4.37bn Gilead Sciences
Avastin $7.21bn Roche	Seretide / Advair $4.36bn GlaxoSmithKline
Remicade $7.16bn J&J / Merck / Mitsubishi Tanabe	Tecfidera $5.23bn Biogen
Xarelto $6.54bn Bayer/ J&J	Stelara $4.01bn J&J

Source: Igea, company reports

The World's Top Consumer Health Companies in 2017

Johnson & Johnson $13.6bn	Reckitt Benckiser $6.9bn
GlaxoSmithKline $10.5bn	Sanofi $4.8bn
Amway $8.6bn	Herbalife $4.4bn
Procter & Gamble $7.5bn	Pfizer $3.5bn
Bayer $7.0bn	Nature's Bounty $3.3bn

Source: Igea, company reports; includes skincare, personal care, oral care, nutritionals, vitamins & hygiene

The World's Top Animal Healthcare Companies in 2014

Zoetis (ex-Pfizer) 20% global share	Merial (Sanofi) 12%
Elanco/Novartis AH (Eli Lilly & Co) 15%	Bayer 7%
Merck & Co 14%	Boehringer Ingelheim 6%

Source: PwC

Top US OTC Products in 2013 by sales

Advil (Pfizer) $615m	Alcon (Novartis) $447m	Dr Scholl's (Merck*) $370m
Nature Made $596m	Claritin (Merck*) $430m	Aleve (Bayer) $364m
Mucinex (Reckitt) $578m	Depend (Kimberly-Clark) $393m	Prilosec OTC (P&G) $359m
Ensure (Abbott) $496m	Poise (Kimberly-Clark) $379m	5 Hour Energy $332m

* Bayer from 2014. Source: Main products including biggest variants; IRI 52 wks to Jan 2014 all channels, Drugstorenews

Other companies profiled in Adbrands

Bausch Health (formerly Valeant)

Astellas Pharma

Gone But Not (Completely) Forgotten

Warner-Lambert	Smithkline Beecham
Wyeth	Aventis
Schering-Plough	Pharmacia